![]() ![]() The health provider suggests that those prescribed Atorvastatin should only drink the juice in small quantities, with the recommendation of below 1.2 litres a day. It warns that those taking certain stations should not combine such medication with grapefruit juice, with doctors advising patients to "avoid it completely or only consume small quantities."Ĭurrently, the NHS states that it is safe to consume grapefruit products if you're taking Fluvastatin, Pravastatin or Rosuvastatin. This means that the medication may be more 'active' than intended with the NHS explaining that "this can increase the risk of side effects or alter the effect the medicine has." Health experts state that grapefruit contains a chemical that interferes with the body's ability to break down medication, known as drug metabolism. The citrus fruit typically increases the level of medication in the blood, particularly when taken in juice form. There's a history of concern regarding grapefruit consumption and its effect on prescription medication. Grape seed extract is not associated with side effects and there are no reported interactions between grape seed extract and any medications or supplements.Health officials have often warned against consuming grapefruit juice whilst on statins (Image: Getty Images/iStockphoto) Take the grape seed supplement for a full 12 weeks to get optimal results. The proper grape seed extract dosage is to take 300 mg once a day or split the dose. To take advantage of this natural compound for lowering blood pressure and cholesterol, look for grape (vitis vinifera) seed extract, standardized to contain at least 92%-95% polyphenols (including OPCs). Grape seed extract is one of the most powerful antioxidants yet discovered. The blood pressure of those in the placebo group did not change. Participants who took the grape seed extract reduced their systolic blood pressure by an average of 8 mmHg and diastolic blood pressure by 5 mmHg. ![]() In the second study, 32 participants with prehypertension (systolic blood pressure of 120-139 mmHg or a diastolic blood pressure of 80-89 mmHg) were randomly assigned to receive grape seed extract (300 mg per day) or placebo for eight weeks. The grape seed extract also decreased the oxidation of LDL particles, lowering the subjects’ risk of atherosclerosis. ![]() Those in the grape seed extract group experienced average blood pressure reductions of 12 mmHg systolic and 8 mmHg diastolic while those in the placebo group saw no changes. In the first study, 300 mg per day of grape seed extract (MegaNatural BP by Polyphenolics-a patented extract) lowered both the systolic and diastolic blood pressures compared to placebo in subjects with metabolic syndrome. Two studies performed at the University of California Davis, one in people with metabolic syndrome and one in people with prehypertension, both found that grape seed extract lowers both systolic (the top number) and diastolic (the bottom number) blood pressure. When taken as a supplement, GSE has also been shown to significantly lower blood pressure, in some small studies. Grape Seed Extract Benefits for High Blood Pressure The study authors concluded that grape seed extract lowers the risk of atherosclerosis and cardiovascular disorders in people with mild cholesterol abnormalities. While triglyceride and very low-density lipoprotein cholesterol were decreased and high-density lipoprotein cholesterol was increased by the grape seed extract, the changes were not statistically significant. The grape seed extract significantly reduced total cholesterol by an average of 10.7 mg/dL, LDL cholesterol by an average of 9.7 mg/dL, and oxidized LDL by an average of 5.5 mg/dL. Fifty-two individuals with mildly high cholesterol were divided into two groups that received either 200 mg/day of grape seed extract or placebo for 8 weeks. Grape seed extract decreased oxidized LDL particles in addition to lowering total and LDL cholesterol in a recent randomized double-blind placebo-controlled study. Oxidized LDL particles play a key role in the formation of arterial plaques and the development of atherosclerosis. Grape Seed Extract Benefits for High Cholesterol More recently, however, researchers have discovered two new roles for OPCs: lowering blood pressure and cholesterol. OPCs from grape seed extract are flavonoids that have been well-known for some time as potent antioxidants that promote blood vessel strength and optimal eye health. Grape seed extract contains a high percentage of compounds called oligomeric proanthocyanidins (OPCs for short). Today, we now know how grape seed extract benefits work to naturally lower blood pressure and cholesterol levels. Six thousand years ago, the Egyptians recognized the healing power of grapes although they didn’t fully understand why the fruit is so beneficial. ![]()
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